Benefits of both CBD and THC

So far the most studied cannabinoids from the cannabis plant are CBD(cannabidiol) and THC(delta-9-tetrahydrocannabinol) What are phytocannabinoids? They are the group of chemical compounds that are specifically found in the cannabis plant. There are over 400 chemical compounds in this special plant and when you are using cannabis you are getting a mixture of all of these natural compounds that work together to balance each other. I wanted to list the benefits of both CBD and THC to give you an idea of the main effects they have on the body. The following lists are from Dr. Bonni Goldstein's new book, Cannabis Revealed, a book I would highly recommend reading as it has science, how to use cannabis, dosing and patient stories...a well rounded book!

CBD EFFECTS

  • NOT psychoactive - no "high" effects
  • Alerting in low doses
  • Reduces pain
  • Relaxes muscle spasms
  • Potent anti-inflammatory
  • Stops nausea/vomiting
  • Reduces anxiety & depression
  • Counters psychotic thoughts
  • Anti-oxidant
  • Anti-convulsant
  • Neuro-protectant
  • Anti-tumor effects

THC EFFECTS

  • Psychoactive
  • Sedating/relaxing
  • Reduces pain
  • Reduces/stops nausea/vomiting
  • Stimulates appetite
  • Induces sleep
  • Reduces anxiety & depression
  • Reduces intraocular eye pressure
  • Anti-oxidant
  • Neuro-protectant
  • Anti-tumor effects

When CBD and THC are used independent of each other, many people of have found relief from a variety of ailments, but when they are used together, it is called "The Entourage Effect", meaning that the cannabinoids work better together than isolated from one another...an example that Dr. Goldstein gives in her book is both THC and CBD when taken separately, have pain relieving properties but there are studies that show CBD enhances pain relief when used together with THC, compared to using THC by itself.

I have had a few members that have been a bit frustrated when they didn't get the relief they wanted from chronic pain issues, but after they added a small amount of THC, the results were much better! If you keep the CBD dose higher than the THC many people do not get the "high" or psychoactive effects but still get the medicinal effects. Finding the right dose and the right combination for you does take a little time, so have fun and experiment with it!

 

Source: https://www.amazon.com/Cannabis-Revealed-m...

The Entourage Effect with Video Demonstration....

This article was taken from leafscience.com, September 11, 2014.

The interaction of various compounds in marijuana is known as the ‘entourage effect.  The‘entourage effect’ was a term coined by Dr. Ethan Russo, who, in 2011, published a paper in the British Journal of Pharmacology describing the synergistic contributions of other compounds in cannabis. A very interesting video is shown below to demonstrate the effect.

Here’s how it works.

Marijuana, unlike most modern day medicine, contains a wide range of chemical compounds. Scientists have identified over 60 unique molecules in cannabis known as cannabinoids, which include THC and CBD. Many other non-cannabinoid compounds are produced by the plant that also have regulatory effects.

For example, terpenes, the molecules responsible for marijuana’s smell, have been shown to block some cannabinoid receptor sites in the brain while promoting cannabinoid binding in others. As a result, terpenes are believed to affect many aspects of how the brain takes in THC or CBD, while offering various therapeutic benefits of their own.

In fact, while THC has gotten most of the attention, studies suggest many of the compounds in marijuana work together to produce a synergy of effects. This is known as the ‘entourage effect.’

Understanding Strains

Marijuana comes in thousands of different varieties, or strains. Different marijuana strains have vastly different chemical profiles that cause different experiences in the same person.

This explains why sometimes marijuana can make a person feel calm, while other times it can make that same person feel anxious or paranoid.

The chemical components of marijuana include, but are not limited to, terpenes, ketones, esters, lactones, alcohols, fatty acids, and steroids. The effects of all these chemicals working together and regulating each other will be much different than the effects of any one chemical working alone.

In other words, marijuana is made up of thousands of different chemicals that work together to produce some general effect. Change the recipe and you change the effect.

The Entourage Effect — An Example

One of the starkest examples of the entourage effect was a British study that gave patients pure THC intravenously one day, and then a mixture of THC and CBD intravenously a week later.

Nicky Taylor, the host of the BBC documentary “Should I Smoke Dope?,” participated in the study and filmed it for the world to see:

Intravenous THC & CBD Experiment

Although she kept referring to cannabidiol (CBD) inaccurately as “cannabinoid,” the end result was so illustrative of the entourage effect that it’s hard to be too annoyed.

In the video, she reported feeling horrible with just THC, “like being at a funeral.” Yet with the THC/CBD mixture, she was unable to contain her laughter throughout the session. THC and CBD appeared to interact somehow, which has been shown by other studies as well.

Incidentally, she was kept blind to which cannabinoid mixture she was given.

Source: http://www.leafscience.com/2014/09/11/medi...